Prostate segmentation and surface reconstruction

We present the instructions for a MRI prostate segmentation and surface reconstruction model that facilities the validation of multi-parametric MRI with histopathology slides from radical prostatectomy specimens and targeted biopsy specimens. Application of this technique combines image processing and computer aided design to construct a high resolution 3D prostate surface from MRI images in three orthogonal views with non-isotropic voxel resolution. The segmentation tool is from MIPAV software, which is freely available and open source.

The proposed model has three major building blocks: 1) Semi-automatic B-Spline registration-guided segmentation model, 2) Ball-pivoting and Poisson based 3D surface reconstruction, and 3) 3D printing for prostate mold. The proposed model is shown in Figure 1.